Today Natsume made this announcment:

Natsume Inc.
Today we are revealing an exclusive to you, our most loyal fans. We are happy to announce Harvest Moon: The Tale of Two Towns for the DS *and* 3DS coming later this year! Fill up your watering can and sharpen your hoe, because it's time for an all-new farming adventure! More details to come in the near future, including some exciting news at E3.

We at HMP are excited for this release and we will be keeping an eye on news reports for possible release dates and more! So keep an eye out for new reports on the News feed here.